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BioPure Article Summary Effect of MTAD on Enamel and Dentin

BioPure™ MTAD™ Antibacterial Root Canal Cleanser Scientific Study Summary

Effect of MTAD on Some Physical Properties of Enamel and Dentin

Entire study published in the Journal of Endodontics
Vol. 29, No. 4, April 2003, T.K. Machnick, C. Munoz, S. Shabahang, M. Torabinejad

Overview
Recently, a mixture of tetracycline, an acid, and a detergent (MTAD) has been advocated to remove smear layer and disinfect canals.

Purpose
The purpose of this study was to evaluate the effect of MTAD on the bond strength to enamel and dentin, as well as its effect on the flexural strength and modulus of elasticity of dentin.

Materials and Methods

  1. Immediate enamel and dentin sheer bond strength was tested. Before bonding composite using Optibond Solo Plus, one of the following surface treatments was used:
    • 1 minute NaOCl (5.25%)/1 minute EDTA (17%)
    • 1 minute NaOCl (5.25%)/1 minute MTAD
    • 30-second etch with H3PO4 (positive control)
    • 2 minutes saline (negative control)
    • 20 minutes NaOCl (1.3%)/5 minute MTAD (clinical protocol for MTAD)
  2. Dentin bars were prepared and randomly assigned to two groups. One group was treated with the clinical protocol for MTAD and the other group was treated with saline. The flexural strength and modulus of elasticity of the specimens were recorded. Data was analyzed using ANOVA and the Student-Newman-Keuls tests.

Conclusion
Surface pre-treatment with acid etch resulted in the greatest enamel bond strengths. All surface pre-treatments were superior to saline for dentin bonding. Results indicated that MTAD could be used as prescribed for clinical use without affecting the tested physical properties of the tooth structure.